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Sobin Kim
Address: 599 Taylor Road
  Piscataway, NJ 08854
Room: BME-207
Phone: 848-445-6558
Email: sobinkim AT rci.rutgers.edu
 
In our laboratory, we develop novel methods for the analysis of nucleotide variations in the genome and apply them in the identification of genetic factors that are linked to common human diseases such as autoimmune diseases, cancers and cardiovascular diseases. We are currently investigating several DNA analysis methods based on MALDI-TOF (Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight) mass spectrometry. Utilizing a molecular affinity system, these high throughput methods allow effective characterization of genetic variations such as SNPs (Single Nucleotide Polymorphisms) and various mutations.
Recent Papers:

1.   Kim, S., M.E. Ulz, T. Nguyen, C. Li, B. Tycko and J. Ju (2004). "Digital high-throughput multiplex genotyping in human tumors." Genomics 83:924-931.

2.   Kim, S., H.D. Ruparal, T.C. Gilliam and J. Ju (2003). "Digital genotyping using molecular affinity and mass spectrometry." Nature Review Genetics 4:1001-1008.

3.   Kim, S., S. Shi, T. Bonome, M.E. Ulz, J.R. Edwards, H. Fodstad, J.J. Russo and J. Ju (2003). "Multiplex genotyping of the human beta2-adrenergic receptor gene using solid phase capturable dideoxy nucleotides and mass spectrometry." Analytical Biochemistry 316:251-258.


CurentNews
Graduate Student Wins P.E.O. Scholar Award

March 25, 2015

BME PhD student Kathryn Drzewiecki has recently been awarded a $15k P.E.O (Philanthropic Educational Organization) Scholar Award. The P.E.O. Sisterhood is interested in bringing increased opportunities...
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Graduate Student Awarded 2-Year NJCCR Fellowship

March 04, 2015

Michelle Sempkowski, a BME PhD student, has been awarded a 2-year, $50,000 fellowship from the New Jersey Commission on Cancer Research. Michelle is currently studying a new binding geometry on...
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Professors Roth and Devore Issued Patent

February 24, 2015

A patent entitled \"Graft Polymers for Enhanced Intracellular Delivery of Antisense Molecules\" was issued to Professors Charles Roth (BME/CBE Departments) and David Devore (NJ Center for Biomaterials)....
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Professors Roth, Uhrich and Team Issued Patent

February 24, 2015

A patent entitled \"Amphiphilic Macromolecules for Nucleic Acid Delivery\" was issued recently to Professors Kathryn Uhrich (CCB), Charles Roth (BME/CBE), along with former Ph.D. students Sarah...
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