Bavigation Bar
quick links
Calendar Calendar of Events
Journal Articles & Publications
highlights

contribute
Judith A. Neubauer
Address: Division of Pulmonary & Critical Care Medicine
  One Robert Wood Johnson Place New Brunswick, NJ 08903
Room:
Phone: 732 235-8961
Email: neubauer@umdnj.edu
 
Studies determining mechanisms involved in modulation of hypoxic chemosensitivity are important for understanding changes in ventilatory control and sympathetic activity associated with conditions resulting in chronic sustained and intermittent hypoxia such as Obstructive Sleep Apnea. Chronic hypoxia (CH) and chronic intermittent hypoxia (CIH) result in changes in sympathetic and respiratory responses to acute hypoxia which we propose arise because of adaptations in the hypoxic sensitivity of the C1 sympathoexcitatory and the pre-B├?┬Âtzinger complex (pre-B├?┬ÂtC) located in the rostral ventrolateral medulla (RVLM). These two regions have been shown to be sensitive to hypoxia increasing sympathetic activity or producing sighs and gasps in response to local hypoxia. Our work has established that this hypoxic sensitivity is dependent on the activity of the oxygen sensing enzyme heme oxygenase (HO). The induction of HO-1 closely corresponds to the restoration of the sympathetic and sigh responses to prolonged exposure to hypoxia. We are interested in understanding the mechanisms controlling the induction of HO-1 in these RVLM regions and how HO regulates respiratory and sympathetic responses through changes in their sensitivity brain hypoxia.
Recent Papers:

1.  

2.  

3.  

Dr. Neubauer`s PubMed


CurentNews
BME Faculty Members Promotion and Reappointment

April 07, 2014

Faculty promotions and reappointment have been announced. The Rutgers Board of Governors has approved promotions of Professors Ioannis (Yannis) Androulakis and David Shreiber to Professor rank effective...
read more >

BME Graduate Student Wins Postdoctoral Fellowship Award

April 02, 2014

Melissa Przyborowski Olekson has been awarded a 1-year, $48,000 National Research Council Postdoctoral Research Fellowship Award to carry her proposed project \"Biofilms Impaired Wound Healing\"...
read more >

Agnes Yeboah Awarded "Faculty for the Future" Fellowship

March 31, 2014

Graduate student, Agnes Yeboah, was awarded a 1-year, Schlumberger Foundation \"Faculty for the Future\" Fellowship to complete her PhD studies on developing an enhanced nanoparticle-based wound...
read more >

Alvin Chen Awarded NIH F31 Grant

March 21, 2014

BME graduate student, Alvin Chen, was awarded a 2-year, $66,230, NIH F31 Predoctoral Fellowship to support his PhD dissertation project entitled, \"A Low-Cost Compact and Portable Robot for Autonomous...
read more >

 

More News >>

 

Rutgers

Rutgers

Home Introduction People Education Research News Contact Visit Rutgers Search Rutgers New Brunswick Login Calendar Recent Journals & Publications Contribute to Biomedical Engineering