Bavigation Bar
quick links
Calendar Calendar of Events
Journal Articles & Publications
highlights

contribute
Judith A. Neubauer
Address: Division of Pulmonary & Critical Care Medicine
  One Robert Wood Johnson Place New Brunswick, NJ 08903
Room:
Phone: 732 235-8961
Email: neubauer@umdnj.edu
 
Studies determining mechanisms involved in modulation of hypoxic chemosensitivity are important for understanding changes in ventilatory control and sympathetic activity associated with conditions resulting in chronic sustained and intermittent hypoxia such as Obstructive Sleep Apnea. Chronic hypoxia (CH) and chronic intermittent hypoxia (CIH) result in changes in sympathetic and respiratory responses to acute hypoxia which we propose arise because of adaptations in the hypoxic sensitivity of the C1 sympathoexcitatory and the pre-B�¶tzinger complex (pre-B�¶tC) located in the rostral ventrolateral medulla (RVLM). These two regions have been shown to be sensitive to hypoxia increasing sympathetic activity or producing sighs and gasps in response to local hypoxia. Our work has established that this hypoxic sensitivity is dependent on the activity of the oxygen sensing enzyme heme oxygenase (HO). The induction of HO-1 closely corresponds to the restoration of the sympathetic and sigh responses to prolonged exposure to hypoxia. We are interested in understanding the mechanisms controlling the induction of HO-1 in these RVLM regions and how HO regulates respiratory and sympathetic responses through changes in their sensitivity brain hypoxia.
Recent Papers:

1.  

2.  

3.  

Dr. Neubauer`s PubMed


CurentNews
Professor John Li Elected IEEE Princeton Engineering in Medicine and Biology Chair

October 16, 2014

BME Distinguished Professor John K-J. Li has been elected to serve on the Executive Committee of the IEEE Region I Princeton-Central Jersey Section. He will take on the role of Chairman of the Engineering...
read more >

Dr. Serom Lee Wins Best Poster

October 15, 2014

Recent BME PhD graduate, Dr. Serom Lee, was awarded first prize in the poster competition at the Innovations in Dermatological Sciences 2014 Conference held at the Heldrich Hotel in New Brunswick,...
read more >

Professor John Li Invited to Serve as Associate Editor for IEEE

October 08, 2014

BME Distinguished Professor John K-J. Li was invited to serve as an Associate Editor for the publication of the 2014 Proceedings of IEEE Engineering in Medicine and Biology Society (EMBS) International...
read more >

Rutgers Team Receives a $2M NIH Grant for Graduate and Postgraduate Training

September 22, 2014

A team of Rutgers faculty led by Professor Martin Yarmush is one of seven new groups in the country selected by the NIH to receive this year`s BEST Award a 5-year $2 million grant designed to...
read more >

 

More News >>

 

Rutgers

Rutgers

Home Introduction People Education Research News Contact Visit Rutgers Search Rutgers New Brunswick Login Calendar Recent Journals & Publications Contribute to Biomedical Engineering