Bavigation Bar
quick links
Calendar Calendar of Events
Journal Articles & Publications
highlights

contribute
Judith A. Neubauer
Address: Division of Pulmonary & Critical Care Medicine
  One Robert Wood Johnson Place New Brunswick, NJ 08903
Room:
Phone: 732 235-8961
Email: neubauer@umdnj.edu
 
Studies determining mechanisms involved in modulation of hypoxic chemosensitivity are important for understanding changes in ventilatory control and sympathetic activity associated with conditions resulting in chronic sustained and intermittent hypoxia such as Obstructive Sleep Apnea. Chronic hypoxia (CH) and chronic intermittent hypoxia (CIH) result in changes in sympathetic and respiratory responses to acute hypoxia which we propose arise because of adaptations in the hypoxic sensitivity of the C1 sympathoexcitatory and the pre-B�¶tzinger complex (pre-B�¶tC) located in the rostral ventrolateral medulla (RVLM). These two regions have been shown to be sensitive to hypoxia increasing sympathetic activity or producing sighs and gasps in response to local hypoxia. Our work has established that this hypoxic sensitivity is dependent on the activity of the oxygen sensing enzyme heme oxygenase (HO). The induction of HO-1 closely corresponds to the restoration of the sympathetic and sigh responses to prolonged exposure to hypoxia. We are interested in understanding the mechanisms controlling the induction of HO-1 in these RVLM regions and how HO regulates respiratory and sympathetic responses through changes in their sensitivity brain hypoxia.
Recent Papers:

1.  

2.  

3.  

Dr. Neubauer`s PubMed


CurentNews
Graduate Student Work Featured in Symbolia Magazine

April 15, 2015

In late January-early February 2015, BME PhD student Maria Qadri had her research covered in a comic journalism feature for Symbolia Magazine. The series can be viewed publicly via the Pacific...
read more >

Cardiovascular Engineering Lab Student Won American Society of Hypertension Young Investigator Award

April 11, 2015

The American Society of Hypertension (ASH) has announced that Timothy Phan from BME`s Cardiovascular Engineering Lab is a recipient of the 2015 Young Investigator Travel Award. Tim will present...
read more >

Professor Roth to Receive One of the 2015 SoE Awards

April 10, 2015

BME/CBE Professor Charles Roth has been selected as the School of Engineering\'s (SoE) 2015 Outstanding Engineering Faculty Award recipient. This award recognizes the special achievements and contributions...
read more >

Graduate Student Awarded Schlumberger Faculty for the Future Fellowship

April 08, 2015

BME graduate student, Ayesha Aijaz, has been awarded a 1-year, Schlumberger Foundation \"Faculty for the Future\" Fellowship to pursue PhD studies on developing a cell-based therapy for chronic...
read more >

 

More News >>

 

Rutgers

Rutgers

Home Introduction People Education Research News Contact Visit Rutgers Search Rutgers New Brunswick Login Calendar Recent Journals & Publications Contribute to Biomedical Engineering