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Frederick H. Silver
Address: Department of Pathology and Laboratory Medicine
  675 Hoes Lane, Piscataway, NJ 08854
Room: R204
Phone:
Email: fhsilver AT hotmail.com
 
Biomaterials, Biomechanics, Mechanotransduction and Medical Devices Extracellular matrix (ECM) is found in both vertebrates and invertebrates and forms the structural scaffold of all tissues and organs. The components of ECM include collagen fibers, proteoglycans, elastic fibers and cells. My laboratory is interested in understanding how these components are assembled into multifunctional tissues that allow mammals to locomote, heal when wounded and store energy through mechanotransduction. Our studies focus on the relationship between structure and properties of ECMs and the use of tissue engineered ECMs as implants. We are also interested in changes in mechanotransduction with age that may lead to impaired healing and disease.
Recent Papers:

1.   Landis, W.J., and Silver, F.H. 2009. Mineral deposition in the extracellular matrices of vertebrate tissues: identification of possible apatite nucleation sites on type I collagen. Cells Tissues Organs. 2009;189(1-4):20-4.

2.   Seehra, G.P., and Silver, F.H. 2006. Viscoelastic properties of acid- and alkaline-treated human dermis: a correlation between total surface charge and elastic modulus. Skin Res Technol. 2006 Aug;12(3):190-8.

3.   Freeman, J.W., and Silver, F.H. 2005. The effects of prestrain and collagen fibril alignment on in vitro mineralization of self-assembled collagen fibers. Connect Tissue Res. 2005;46(2):107-15.

Website


CurentNews
Graduate Student Work Featured in Symbolia Magazine

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In late January-early February 2015, BME PhD student Maria Qadri had her research covered in a comic journalism feature for Symbolia Magazine. The series can be viewed publicly via the Pacific...
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Cardiovascular Engineering Lab Student Won American Society of Hypertension Young Investigator Award

April 11, 2015

The American Society of Hypertension (ASH) has announced that Timothy Phan from BME`s Cardiovascular Engineering Lab is a recipient of the 2015 Young Investigator Travel Award. Tim will present...
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Professor Roth to Receive One of the 2015 SoE Awards

April 10, 2015

BME/CBE Professor Charles Roth has been selected as the School of Engineering\'s (SoE) 2015 Outstanding Engineering Faculty Award recipient. This award recognizes the special achievements and contributions...
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Graduate Student Awarded Schlumberger Faculty for the Future Fellowship

April 08, 2015

BME graduate student, Ayesha Aijaz, has been awarded a 1-year, Schlumberger Foundation \"Faculty for the Future\" Fellowship to pursue PhD studies on developing a cell-based therapy for chronic...
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