Bavigation Bar
quick links
Calendar Calendar of Events
Journal Articles & Publications
highlights

contribute
Stavroula Sofou
Address: 599 Taylor Road
  Piscataway, NJ 08854
Room: BME-219
Phone: 848-445-6568
Email: ss1763 AT rci.rutgers.edu
 
Our group works on Biomembranes and Drug Delivery Systems. We investigate the intermolecular and interfacial interactions determining the morphology and collective properties of self-assembling heterogeneous biomembranes. We use these materials to engineer lipid-based carriers of diagnostics and therapeutics for medical applications. Current projects include: environmentally responsive liposomes to improve transport and trafficking of chemotherapeutics in solid tumors, multifunctional liposomes for antivascular therapy, lipid-based carriers for targeted internal radiotherapy.
Recent Papers:

1.   S. Karve, A. Bandekar, R.M. Ali, S. Sofou, The pH-dependent association with cancer cells of tunable functionalized lipid vesicles with encapsulated doxorubicin for high cell-kill selectivity, Biomaterials, 2010, Vol 31, 4409-4416

2.   S. Karve, A. Alaouie, Y. Zhou, J. Rotolo, S. Sofou, The use of pH-triggered leaky heterogeneities on rigid lipid bilayers to improve intracellular trafficking and therapeutic potential of targeted liposomal immunochemotherapy, Biomaterials, 2009, Vol 30, 6055-6064

3.   M.-Y. Chang, J. Seideman, S. Sofou, Enhanced loading efficiency and retention of 225Ac in rigid liposomes for potential targeted therapy of micrometastases, Bioconjugate Chemistry, 2008, Vol 6, 1274-1282

Website


CurentNews
Annual Review of Biomedical Engineering Ranked No. 1 again by ISI

August 11, 2014

For over a decade, articles in the Annual Review of Biomedical Engineering (ARBME) were cited more often than papers in any of its peer journals, according to ISI`s 2013 Journal Citation Report, giving...
read more >

Organ Storage Breakthrough from the Yarmush Lab Published in Nature Medicine

July 29, 2014

Research performed in Professor Martin Yarmush`s lab at Rutgers University and Massachusetts General Hospital has yielded a novel strategy to extend the time for liver storage. By using a combination...
read more >

Freeman Team Awarded NSF Grant

July 21, 2014

Professor Joseph Freeman, director of the MOTR (Musculoskeletal Tissue Regeneration) Laboratory, just received a 3 year award from the NSF for the project entitled, \"Microelectronically Stimulating...
read more >

BME and MAE Faculty Collaborate on NSF Award for Instrumentation Development

July 21, 2014

BME faculty David Shreiber and Jeffrey Zahn and MAE faculty Hao Lin and Jerry Shan have been awarded an Instrumentation Development for Biological Research (IDBR) grant from the NSF for $425k....
read more >

 

More News >>

 

Rutgers

Rutgers

Home Introduction People Education Research News Contact Visit Rutgers Search Rutgers New Brunswick Login Calendar Recent Journals & Publications Contribute to Biomedical Engineering