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Stavroula Sofou
Address: 599 Taylor Road
  Piscataway, NJ 08854
Room: BME-219
Phone: 848-445-6568
Email: ss1763 AT rci.rutgers.edu
 
Our group works on Biomembranes and Drug Delivery Systems. We investigate the intermolecular and interfacial interactions determining the morphology and collective properties of self-assembling heterogeneous biomembranes. We use these materials to engineer lipid-based carriers of diagnostics and therapeutics for medical applications. Current projects include: environmentally responsive liposomes to improve transport and trafficking of chemotherapeutics in solid tumors, multifunctional liposomes for antivascular therapy, lipid-based carriers for targeted internal radiotherapy.
Recent Papers:

1.   S. Karve, A. Bandekar, R.M. Ali, S. Sofou, The pH-dependent association with cancer cells of tunable functionalized lipid vesicles with encapsulated doxorubicin for high cell-kill selectivity, Biomaterials, 2010, Vol 31, 4409-4416

2.   S. Karve, A. Alaouie, Y. Zhou, J. Rotolo, S. Sofou, The use of pH-triggered leaky heterogeneities on rigid lipid bilayers to improve intracellular trafficking and therapeutic potential of targeted liposomal immunochemotherapy, Biomaterials, 2009, Vol 30, 6055-6064

3.   M.-Y. Chang, J. Seideman, S. Sofou, Enhanced loading efficiency and retention of 225Ac in rigid liposomes for potential targeted therapy of micrometastases, Bioconjugate Chemistry, 2008, Vol 6, 1274-1282

Website


CurentNews
Graduate Student Awarded Society for Biomaterials Student Travel Achievement Recognitions (SFB STARs)

May 19, 2015

BME graduate student, Ayesha Aijaz, was awarded a Society of Biomaterials STAR award for her research at the 2015 SFB meeting. The Student Travel Achievement Recognitions (STARs) recognize research...
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Rutgers NIH Biotechnology Training Program Renewed a Sixth Time

May 19, 2015

The Rutgers PhD Program in Biotechnology has been renewed by the NIH National Institutes of General Medical Sciences for a record sixth time (years 26-30). The 5-year award, totaling $1,987,080 provides...
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BME Staff Robin Yarborough Nominated for Career Mentor of the Year Award

May 18, 2015

BME Department Administrator Robin Yarborough was one of 70 mentors nominated for the University Career Services \"Career Mentor of the Year 2015\" program. Robin was nominated because she gives...
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Professor Freeman Named Chancellor`s Scholar

May 13, 2015

BME Professor Joseph Freeman has been nominated and selected to be named as a Chancellor`s Scholar at Rutgers. The Chancellor`s Scholar initiative was created through the New Brunswick Strategic...
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