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Stavroula Sofou
Address: 599 Taylor Road
  Piscataway, NJ 08854
Room: BME-219
Phone: 848-445-6568
Email: ss1763 AT rci.rutgers.edu
 
Our group works on Biomembranes and Drug Delivery Systems. We investigate the intermolecular and interfacial interactions determining the morphology and collective properties of self-assembling heterogeneous biomembranes. We use these materials to engineer lipid-based carriers of diagnostics and therapeutics for medical applications. Current projects include: environmentally responsive liposomes to improve transport and trafficking of chemotherapeutics in solid tumors, multifunctional liposomes for antivascular therapy, lipid-based carriers for targeted internal radiotherapy.
Recent Papers:

1.   S. Karve, A. Bandekar, R.M. Ali, S. Sofou, The pH-dependent association with cancer cells of tunable functionalized lipid vesicles with encapsulated doxorubicin for high cell-kill selectivity, Biomaterials, 2010, Vol 31, 4409-4416

2.   S. Karve, A. Alaouie, Y. Zhou, J. Rotolo, S. Sofou, The use of pH-triggered leaky heterogeneities on rigid lipid bilayers to improve intracellular trafficking and therapeutic potential of targeted liposomal immunochemotherapy, Biomaterials, 2009, Vol 30, 6055-6064

3.   M.-Y. Chang, J. Seideman, S. Sofou, Enhanced loading efficiency and retention of 225Ac in rigid liposomes for potential targeted therapy of micrometastases, Bioconjugate Chemistry, 2008, Vol 6, 1274-1282

Website


CurentNews
Graduate Student Work Featured in Symbolia Magazine

April 15, 2015

In late January-early February 2015, BME PhD student Maria Qadri had her research covered in a comic journalism feature for Symbolia Magazine. The series can be viewed publicly via the Pacific...
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Cardiovascular Engineering Lab Student Won American Society of Hypertension Young Investigator Award

April 11, 2015

The American Society of Hypertension (ASH) has announced that Timothy Phan from BME`s Cardiovascular Engineering Lab is a recipient of the 2015 Young Investigator Travel Award. Tim will present...
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Professor Roth to Receive One of the 2015 SoE Awards

April 10, 2015

BME/CBE Professor Charles Roth has been selected as the School of Engineering\'s (SoE) 2015 Outstanding Engineering Faculty Award recipient. This award recognizes the special achievements and contributions...
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Graduate Student Awarded Schlumberger Faculty for the Future Fellowship

April 08, 2015

BME graduate student, Ayesha Aijaz, has been awarded a 1-year, Schlumberger Foundation \"Faculty for the Future\" Fellowship to pursue PhD studies on developing a cell-based therapy for chronic...
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