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Stavroula Sofou
Address: 599 Taylor Road
  Piscataway, NJ 08854
Room: BME-219
Phone: 848-445-6568
Email: ss1763 AT rci.rutgers.edu
 
Our group works on Biomembranes and Drug Delivery Systems. We investigate the intermolecular and interfacial interactions determining the morphology and collective properties of self-assembling heterogeneous biomembranes. We use these materials to engineer lipid-based carriers of diagnostics and therapeutics for medical applications. Current projects include: environmentally responsive liposomes to improve transport and trafficking of chemotherapeutics in solid tumors, multifunctional liposomes for antivascular therapy, lipid-based carriers for targeted internal radiotherapy.
Recent Papers:

1.   S. Karve, A. Bandekar, R.M. Ali, S. Sofou, The pH-dependent association with cancer cells of tunable functionalized lipid vesicles with encapsulated doxorubicin for high cell-kill selectivity, Biomaterials, 2010, Vol 31, 4409-4416

2.   S. Karve, A. Alaouie, Y. Zhou, J. Rotolo, S. Sofou, The use of pH-triggered leaky heterogeneities on rigid lipid bilayers to improve intracellular trafficking and therapeutic potential of targeted liposomal immunochemotherapy, Biomaterials, 2009, Vol 30, 6055-6064

3.   M.-Y. Chang, J. Seideman, S. Sofou, Enhanced loading efficiency and retention of 225Ac in rigid liposomes for potential targeted therapy of micrometastases, Bioconjugate Chemistry, 2008, Vol 6, 1274-1282

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CurentNews
Patent Issued to Professor Yarmush and Colleagues

December 12, 2014

A patent was issued to Professor Martin Yarmush, Eric Wallenstein, and Rene Schloss entitled, \"Media Conditioning for Improving Gene Delivery Efficiency To Differentiating Embryonic Stem...
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BME Students in Cardiovascular Engineering Lab Won Aresty Research Assistantships for 2014-2015

November 11, 2014

Three BME students from the Cardiovascular Engineering Lab won Aresty undergraduate research assistantships for the 2014-2015 academic year. Jeanette Caronia is working on Emerging Cardiovascular...
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BME Undergraduate Students Receive Aresty Awards for Fall 2014

November 10, 2014

The following BME undergraduate students were recently awarded grants for their undergraduate research with BME faculty:
1) Christopher Bargoud working with Professor William Craelius...
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Graduate Student Chris Lowe Wins Best Poster at BMES

October 29, 2014

BME PhD Graduate Student Christopher Lowe was awarded the Bioconjugate Chemistry (BC) Best Poster at the BMES Annual Meeting in San Antonio Texas during October 22-25, 2014. Associate Editor Erin...
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