Charles M. Roth

Professor, Department Chair

Phone:848-445-6686
Fax:732-445-3753
Email:cmroth@soe.rutgers.edu
Office: BME-205
Office Hours: By appointment
Website: Charles M. Roth

Education

Postdoctural, Bioengineering, Harvard Medical School, 1995-97
Ph.D., Chemical Engineering, University of Delaware, 1994
B.S.E., Chemical Engineering, University of Pennsylvania, 1989

 

Honors

2015 Outstanding Engineering Faculty Award, Rutgers University

2013 Fellow, American Institute of Medical and Biological Engineering

2011-2017 Member, NIH Gene and Drug Delivery Study Section

2008  Warren I. Susman Award for Excellence in Teaching

2005 Rutgers, FASIP Award for Teaching, Research and Service (ranked first in Department)

2003 NSF Faculty CAREER Award

2002, 2006 Charles & Johanna Busch Biomedical Research Award

2002 Whitaker Foundation Transitional Career Award

2000 Whitaker Foundation Travel Award

1998-99 Harvard Council on Biomedical Engineering Faculty Excellence Fellow

1995-97 NIH Postdoctoral Fellowship

Professional Affiliations

  • Department of Chemical and Biochemical Engineering
  • Graduate Program in Biochemistry
  • Graduate Program in Cell and Developmental Biology
  • New Jersey Center for Biomaterials
  • Cancer Institute of New Jersey
     

Research Interests

Our research involves the application of molecular and nanobioengineering approaches to cancer, infection, and other biomedical problems. Much of our work centers on the development of technology for efficient delivery of oligonucleotides (antisense or short interfering RNA) for gene silencing and antimicrobial drugs for infection control. Current projects include: (1) aerosolized nanomedicine for lung infections; (2) nanomaterials for antimicrobial drug delivery to wounds; (3) physiologically based pharmacokinetic modeling of nanomedicines.

Selected Publications

1. Kantamneni H, Zevon M, Donzanti MJ, Zhao X, Sheng Y, Barkund SR, McCabe LH, Banach-Petrosky W, Higgins LM, Ganesan S, Riman RE, Roth CM, Tan M-C, Pierce MC, Ganapathy V, Moghe PV. Surveillance nanotechnology for multi-organ cancer metastases. Nature Biomed. Engr., 2017; 1:993-1003; doi:10.1038/s41551-017-0167-9.
2. Nusblat LM, Carroll MJ, Roth CM, Cross talk between M2 macrophages and glioma stem cells. Cell Oncol., 2017; 40:471-482; DOI 10.1007/s13402-017-0337-5.
3. Gu L, Wang N, Nusblat LM, Soskind R, Roth CM, Uhrich KE.  pH-responsive amphiphilic macromolecular carrier for doxorubicin delivery. J. Bioactive Compatible Polymers, 2017; 32:3-16; doi: 10.1177/0883911516643219.