Professor Martin Yarmush received a 4-year $2,578,970 grant from the National Institute for Biomedical Imaging and Bioengineering to develop a novel subzero non-freezing protocol to extend the viable preservation times of hepatic tissues and organs using a supercooled medium. The work intends to generate a new field of supercooled storage, and also establish quantitative standards for evaluating the organ viability following preservation. While the focus of the current work is on the liver, the protocols established will also serve as the basis for subzero nonfreezing preservation of all organs and tissue engineered products.