A patent was issued to Professors Martin Yarmush and Tania Konry (at Northeastern University) entitled, "Amplifying Rare Cell Surface Markers (US Patent number: 10054591). The invention describes systems and methods for detecting molecules secreted from a single cell, as well as rare cell surface markers. The systems and methods include using rolling circle amplification with microfluidic devices for encapsulation, incubation, and analysis of these molecules.